NanoB2A Group

NanoBiosensors and Bioanalytical Applications

The Biodeposition and Biodetection Unit - U4 NANBIOSIS has been updated with new equipment and components with ERDF funds

Published: March 24, 2021

The Unit of Biodetection belonging to the U4- NANBIOSIS has been recently upgraded with new optics and microfluidic components to improve its performance and increase its competitiveness with other similar equipment in the market.

The Unit of Biodetection, a Surface Plasmon Resonance (SPR) biosensor, available at the Unit is a highly sensitive device that allows the monitoring of biomolecular interactions in a real time label-free configuration.The optical device is based on the detection of the refractive index changes occurring in the sensing surface (i.e. metallic surface), which in turn can be related to mass changes as those occurring as a result of binding/desorption processes. With this actuation, some components have been updated (i.e. flow injection pimps, light sources, and spectrophotometer for signal output, among others)  in order to increase the performance of the current design.

The equipment has been cofinanced by the European Regional Development Fund (ERDF) through the Pluriregional Operational Program of Spain (POPE) 2014-2020

The ERDF funding was also used to update the UV/O3 Cleaner of the Biodeposition Unit belonging to the same NANBIOSIS Unit 4

You can see a summary of these actions here

Let's start the CoNVat against coronavirus!

Published: March 5, 2020

Our CoNVat project for new coronavirus diagnostics has been granted! The NanoB2A group will lead and coordinate a European research project to provide a point-of-care biosensor for the rapid detection of coronavirus. CoNVat is one of the 17 projects selected by the European Commission to be funded as urgent response to control and manage the COVID-19 outbreak.

Besides NanoB2A, CoNVat will engage top researchers in the fields of virology, clinical diagnostics, and epidemiology from Spain, France, and Italy. The group of Prof. Jordi Serra Cobo from the University of Barcelona provides an extensive experience in the study and epidemiology of coronavirus in reservoir animals and vectors. In France, the laboratory of Prof. Remi Charrel in the Aix-Marseille University is leader in virology and molecular biology, pioneering the development and production of biological material for the validation of new diagnostic systems. Finally, CoNVat also counts on the Italian National Institute of Infectious Diseases (INMI), the reference institute for the analysis and diagnosis of COVID-19. Researchers from Prof. Antonino di Caro's laboratory were among the first to isolate and sequence the human SARS-CoV-2 coronavirus.

With a duration of two years, the project aims to develop an advanced diagnostics system for real-time detection and identification of SARS-CoV-2 and other coronaviruses in both humans and reservoir species. The POC biosensor will be based on our proprietary nanophotonic technology (the BiMW interferometers) that enables ultrasensitive analysis of body fluids in few minutes and label-free fashion. The CoNVat system will be optimized and validated for a rapid population screening and identification of the new coronavirus among other clinically relevant viruses, like influenza. But further, the project will extend beyond the current pandemic and human diagnosis. The CoNVat biosensor will also be used for the analysis of different types of coronaviruses present in reservoir animals, such as bats, in order to observe and monitor possible evolutions of these viruses and prevent future outbreaks in humans.

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