NanoB2A Group

NanoBiosensors and Bioanalytical Applications


The NanoB2A group is a multidisciplinary research team led by Prof. Laura M. Lechuga. We are physicists, engineers, chemists, and biologists working in the broad field of Nanobiotechnology. Our motivation is to develop new and cutting-edge biosensor nanotechnologies using photonics, one of the key technologies of the 21st century, to promote and boost healthcare and well-being for our society.

NanoB2A Group


Our research focuses on the development of photonic point-of-care biosensors and their employment in clinical, biomedical, and environmental areas. We mainly exploit Nanoplasmonics and Silicon Nanophotonics technologies to accomplish integrated biosensing systems for the label-free, real-time, and multiplexed analysis at the point of care. Our activity encompasses the entire process of generating new biosensor devices, including fundamental research and theoretical design, nanofabrication, surface biofunctionalization, lab-on-a-chip integration, and their final validation in real scenarios.


ICN2 Building

NanoB2A group is established at the Catalan Institute of Nanoscience and Nanotechnology (ICN2), in Barcelona (Spain), belonging to the CERCA network of Catalan Research Institutes and integrated in BIST (Barcelona Institute of Science and Technology). The NanoB2A belongs as well to the Spanish National Research Council (CSIC) and the Networking Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN).

ICN2 Building


The Biodeposition and Biodetection Unit - U4 NANBIOSIS has been updated with new equipment and components with ERDF funds

The Unit of Biodetection belonging to the U4- NANBIOSIS has been recently upgraded with new optics and microfluidic components to improve its performance and increase its competitiveness with other similar equipment in the market.

The Unit of Biodetection, a Surface Plasmon Resonance (SPR) biosensor, available at the Unit is a highly sensitive device that allows the monitoring of biomolecular interactions in a real time label-free configuration.The optical device is based on the detection of the refractive index changes occurring in the sensing surface (i.e. metallic surface), which in turn can be related to mass changes as those occurring as a result of binding/desorption processes. With this actuation, some components have been updated (i.e. flow injection pimps, light sources, and spectrophotometer for signal output, among others)  in order to increase the performance of the current design.

The equipment has been cofinanced by the European Regional Development Fund (ERDF) through the Pluriregional Operational Program of Spain (POPE) 2014-2020

The ERDF funding was also used to update the UV/O3 Cleaner of the Biodeposition Unit belonging to the same NANBIOSIS Unit 4

You can see a summary of these actions here

Biosensors for Pandemics - Online Conference on May 6th

At the ICN2, together with Phantoms Foundation, we are organizing the first online conference about COVID19 pandemics. The Biosensors for Pandemics Conference will be streamed worldwide on May 6th, joining top international researchers to discuss how new nanotech diagnostic systems can help in health emergency situations.

Prof. Laura M. Lechuga will give a Keynote presentation about the CoNVat project and how our advanced nanobiosensing platforms are being developed for point-of-care diagnostics and surveillance of coronavirus. 

Visit the Conference Website and join us:


Featured article in OPN - OSA magazine

The current issue of Optics & Photonics News, the prestigious outreach journal of The Optical Society (OSA), highlights in the cover our recent publication Nanophotonic Biosensors: Driving Personalized Medicine.

In this feature, we provide a clear and understandable overview of the latest advances in optical biosensing platforms and their applications in healthcare. Photonic biosensors are a unique solution to accomplish more informative, timely and precise diagnosis of human diseases, and recently, they are also emerging as alternative tools to help in the development and general widespread of personalized therapies.

Have a look!

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