Towards an Integrated Optofluidic System for Highly Sensitive Detection of Antibiotics in Seawater Incorporating Bimodal Waveguide Photonic Biosensors and Complex, Active Microfluidics.

C. Szydzik, A.Fdez-Gavela, J. Roccisano, S. Herranz, A. Mitchell, and L.M. Lechuga

SPIE Proceedings, SPIE Biophotonics Australasia , 2016 - DOI: 10.1117/12.2242885

Abstract: We present recent results on the realisation and demonstration of an integrated optofluidic lab-on-a-chip measurement system. The system consists of an integrated on-chip automated microfluidic fluid handling subsystem, coupled with bimodal nano-interferometer waveguide technology, and is applied in the context of detection of antibiotics in seawater. The bimodal waveguide (BMWG) is a highly sensitive label-free biosensor. Integration of complex microfluidic systems with bimodal waveguide technology enables on-chip sample handling and fluid processing capabilities and allows for significant automation of experimental processes. The on-chip fluid-handling subsystem is realised through the integration of pneumatically actuated elastomer pumps and valves, enabling high temporal resolution sample and reagent delivery and facilitating multiplexed detection processes. © (2016) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.

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