Magneto-optic sensitivity enhancement in plasmonic sensors
B. Sepúlveda, A. Calle, L.M. Lechuga and G. Armelles
BioWorld Europe (The magazine for the life science industry in Europe), 1, 2008, 12-14
Abstract: The sensitivity and limit of detection of the SPR sensors are still not enough for the direct detection of very low concentration of low weight molecules, as for example some pathogens or pollutants, the detection of single nucleotide polymorphisms in DNA, or protein detection at femtomolar level. Recently, several SPR configurations have been described to improve these limits of detection as, for example, the phase sensitive SPR based on a Mach-Zehnder configuration (Yu et al. 2004), the differential ellipsometric SPR (Hooper et al. 2004) or the optical heterodyne SPR (Kuo et al. 2003).
As an alternative, we are investigating a new Magnetooptical Surface Plasmon Resonance bisensor (MOSPR) (Sepulveda et al. 2006) which can improve the sensitivity of the conventional Surface Plasmon Resonance (SPR) sensors.