Integration of bio, nano, micro and cogno in biosensor devices for human health applications

L. M. Lechuga, A. Calle and C. Domínguez

Superficies y Vacio, 18, 2006, 1-6

http://www.redalyc.com/src/inicio/ArtPdfRed.jsp?iCve=94218401

Abstract: The design, fabrication and testing of micro/nanobiosensor devices based on optoelectronics and nanomechanical highly sensitive transducers is shown. Most of the devices are fabricated by standard silicon CMOS microelectronics technology after a precise design for achieving a high sensitivity for biosensing applications. Three biosensors have been developed: (a) a Surface Plasmon Resonance biosensor (b) an integrated Mach-Zehnder interferometer micro/nanodevice based on optical waveguides and (c) nanomechanical biosensors based on microcantilevers. Direct biosensing with all the sensors has been tested, after a specific receptor coupling to the surface device using nanometer scale immobilization techniques. Further integration of the micro/nano sensors, the microfluidics, the sources, the photodetectors and the CMOS electronics will render in complete lab-on-a-chip microsystems which could be used in field applications.

Integration of bio, nano, micro and cogno in biosensor devices for human health applications
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